Endocrine Abstracts

Introduction: Phaeochromocytomas (PHEO) are diagnosed with classic findings and symptoms but biochemical confirmation must be made. Either urinary or plasma chatecholamines and metanephrines can be used for biochemical evaluation. Normal values rule out the diagnosis, whereas fourfold increase above the upper limit of normal confirm the diagnosis. But value of borderline or less than fourfold elevations in the diagnosis is not clear. We aimed to determine the urinary fractiona...

Introduction: 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each cells of a male. It occurs in about 1/1000 of newborn boys and most males with this syndrome have normal sexual development and fertility. They tend to have tall stature and mild motor and language developmental problems. Testosterone levels are normal. Increased rate of criminal activity in XYY males was related to a lack of judgement and lower socioeconomic status due to a lower mean ...

Objective: Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting 5–10% of women in reproductive period. Our goal is to determine which symptoms and findings are the most common in Turkish adolescents with PCOS.Material and method: Ninety three adolescents (15–19 years old) who admitted to our outpatient clinic with at least one of the complaints (acne, obesity, menstrual irregularities and hirsutism) were enrolled in the study....

Introduction: Mitochondrial diseases usually occur by mutations of mitochondrial or nuclear DNA. Mitochondrial cytopathy is a disease affecting many systems including endocrine system. We present a case diagnosed as mitochondrial myopathy previously accompanying multiple endocrinological pathologies.Case: Fifty-two years old female patient admitted in another center with a complaint of drooping of upper eyelids 25 years ago. Acetylcholine receptor antibo...

Introduction: Primary hyperparatyhyroidism (PHPT) is usually caused by single or multiple adenomas and cancer is rare accounting for <1% of all presentations. The presence of certain cytological and architectural features such as adherence to adjacent organs, a solid growth pattern, broad bands of fibrosis, cytological atypia, and an irregular growth contour do not indicate malignancy but are recognised as atypical features encountered more commonly in malignant than benig...

Introduction: Diabetes mellitus (DM) is an endocrine disease characterised by metabolic abnormalities and long-term complications. Achilles tendon (AT) play an important role in foot biomechanics. We aimed to investigate the effect of DM on the AT, which may contribute to the long-term complications in the foot–ankle complex.Materials and methods: 78 diabetic patients with (35 cases) or without (43 cases) diabetic foot ulcers were recruited from End...

Introduction: Increasing evidence is available for the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed up at a single site.Materials and methods: Medical records of 182 patients, diagnosed with prolactinoma, were reviewed retrospectively. Out of these patients, 114 patients (103 female patients, 11 male patients, mean age 35±10.4)...

Introduction: Endocrinological and metabolic changes can occur in critically ill patients, which may affect the prognosis and outcome. The hypothalamic–anterior–pituitary axis (HPA) plays a crucial role in the endocrine regulation of metabolic and immunological homeostasis. In this prospective study, we evaluated the pituitary–adrenal–gonadal–thyroid axis in the adult Intensive Care Unit (ICU) patients,their outcome, the association between these hormo...

Introduction: Neoplasms of the thyroid gland are classified according to the cell that it originates and commonly they originate from follicular or parafollicular C cells. The most common differentiated thyroid cancers (DTC) are papillary and follicular carcinomas. Coexistence of two different histological types of primary follicular thyroid neoplasm is a rare condition. There are previous reports of concomitant medullary and papillary thyroid cancers. However, there is scarce...

Introduction: It is unclear whether ultrasonographic (US) findings and fine-needle aspiration biopsy (FNAB) results of nodules accompanied with Hashimoto’s thyroiditis (HT) are affected by the presence of thyroiditis or not. In this study, we compared US features and cytological results of nodules in patients with and without HT.Methods: Patients who underwent FNAB in our clinic were evaluated prospectively. Nodules in patients with and without HT w...